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Article

Roles of a 106-bp origin enhancer and Escherichia coli DnaA protein in replication of plasmid R6K.

Nucleic acids research - 25 Feb 1992

Wu F, Goldberg I, Filutowicz M

Abstract excerpt

A dnaA 'null' strain could not support replication of intact plasmid R6K or derivatives containing combinations of its three replication origins (alpha, gamma, beta). DnaA binds in vitro to sites in two functionally distinct segments of the central gamma origin. The 277-bp core segment is common to all three origins and contains DnaA box 2, which cannot be deleted without preventing replication. Immediately to...

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Identifiers

PMID: 1627205
DOI: 10.1093/nar/20.4.811
PMCID: PMC312022

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Roles of a 106-bp origin enhancer and Escherichia coli DnaA protein in replication of plasmid R6K.PMID 1627205Read ↗

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