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Article

Replication origin of the broad host range plasmid RK2. Positioning of various motifs is critical for initiation of replication.

The Journal of biological chemistry - 3 Apr 1998

Doran K S, Konieczny I, Helinski D R

Abstract excerpt

The 393-base pair minimal origin, oriV, of plasmid RK2 contains three iterated motifs essential for initiation of replication: consensus sequences for binding the bacterial DnaA protein, DnaA boxes, which have recently been shown to bind the DnaA protein; 17-base pair direct repeats, iterons, which bind the plasmid encoded replication protein, TrfA; and A + T-rich repeated sequences, 13-mers, which serve as the...

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Source

Identifiers

PMID: 9525957
DOI: 10.1074/jbc.273.14.8447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Replication origin of the broad host range plasmid RK2. Positioning of various motifs is critical for initiation of replication.PMID 9525957Read ↗

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Host-dependent requirement for specific DnaA boxes for plasmid RK2 replication.Semantic proximity Read ↗

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