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Article

Differential and opposed transcriptional effects of protein fusions containing the VP16 activation domain.

FEBS letters - 15 Jun 2001

Matis C, Chomez P, Picard J, Rezsohazy R

Abstract excerpt

Overexpression of strong transcriptional activators like herpes simplex virion protein 16 (VP16) may lead to non-specific inhibition of gene expression as a result of the titration of transcription factors. Here we report that a fusion between the homeoprotein Hoxa2 and the VP16 activation domain inhibits transcription from the strong promoter/enhancers of cytomegalovirus (CMV) and Rous sarcoma virus (RSV). A...

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Source

Identifiers

PMID: 11418119
DOI: 10.1016/s0014-5793(01)02532-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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