Article
RBP-J<sub>k</sub>repression activity is mediated by a co-repressor and antagonized by the Epstein-Barr virus transcription factor EBNA2
1 Jan 1995
Abstract excerpt
The Epstein-Barr virus (EBV) protein EBNA2 is a transcriptional activator that can be targeted to its DNA responsive elements by direct interaction with the cellular protein RBP-J kappa. RBP-J kappa is a ubiquitous factor, highly conserved between man, mouse and Drosophila, whose function in mammalian cells is largely unknown. Here we provide evidence that RBP-J kappa is a transcriptional repressor and, more...
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