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Article

The H1 and H2 regions of the activation domain of herpes simplex virion protein 16 stimulate transcription through distinct molecular mechanisms

1 Jan 2002

Abstract excerpt

BACKGROUND: The Herpes Simplex Virion Protein 16 (VP16) contains a strong activation domain which can be subdivided into two regions, H1 and H2, both of which independently activate transcription in vivo. Several components of the basal transcription machinery have been shown to interact with the activation domain of VP16, mostly through the H1 region. RESULTS: We show that the H2 region binds directly to histone...

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Identifiers

PMID: 11856373
DOI: 10.1046/j.1356-9597.2001.00492.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The H1 and H2 regions of the activation domain of herpes simplex virion protein 16 stimulate transcription through distinct molecular mechanismsPMID 11856373Read ↗

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