Article
Induction of AP-2alpha expression by adenoviral infection involves inactivation of the AP-2rep transcriptional corepressor CtBP1.
The Journal of biological chemistry - 27 Jul 2001
Schuierer M, Hilger-Eversheim K, Dobner T, Bosserhoff A K, Moser M, Turner J, Crossley M, Buettner R
Abstract excerpt
AP-2 transcription factors execute important functions during embryonic development and malignant transformation. Recently, we have isolated a transcriptional repressor of AP-2alpha expression, the novel Krüppel-related zinc finger protein AP-2rep (Klf12). Here, we show that repression of AP-2alpha transcription by AP-2rep is dependent on an N-terminal PVDLS motif that interacts specifically with the corepressor...
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