Article
K-ras gene mutations in non-small cell lung cancer in Japanese.
Oncology reports - 1 Jan 2000
Noda N, Matsuzoe D, Konno T, Kawahara K, Yamashita Y, Shirakusa T
Abstract excerpt
To evaluate the association of mutations in the K-ras gene with the incidence of non-small cell lung cancer (NSCLC) in Japanese patients, 410 patients treated surgically were studied. DNA was extracted from frozen specimens, and polymerase chain reaction-sequence specific oligonucleotide probe (PCR-SSOP) hybridization assay was used to examine K-ras mutations in codons 12, 13 and 61. K-ras mutations were found in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
