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Article

Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas.

Virchows Archiv : an international journal of pathology - 1 May 2005

Soung Young Hwa, Lee Jong Woo, Kim Su Young, Seo Si Hyung, Park Won Sang, Nam Suk Woo, Song Sang Yong, Han Joung Ho, Park Cheol Keun, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

Both epidermal growth factor receptor (EGFR) and RAS gene mutations contribute to the development of non-small cell lung cancer (NSCLC). Because RAS is one of the downstream molecules in the EGFR signal transduction, the association between the somatic mutations of EGFR and RAS may be important in the pathogenesis of NSCLC . However, to date, such data are lacking. In this study, we analyzed the hotspot regions...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 15815931
DOI: 10.1007/s00428-005-1254-y

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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