Article
Detection of activated K-ras in non-small cell lung cancer by membrane array: a comparison with direct sequencing.
Oncology reports - 1 Jul 2007
Chong Inn-Wen, Chang Mei-Yin, Sheu Chau-Chyun, Wang Cheng-Yuan, Hwang Jhi-Jhu, Huang Ming-Shyan, Lin Shiu-Ru
Abstract excerpt
The ability to detect K-ras oncogene may provide additional information for the management of patients with non-small cell lung cancer (NSCLC). In the present study, we detected the K-ras oncogene in 76 patients with NSCLC by two methods: direct sequencing of K-ras in tumor tissues and membrane array detection of the gene overexpression specific for activated K-ras in peripheral blood. The results showed that 28...
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