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Article

[K-RAS gene mutations in patients with non-small cell lung cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Jun 2010

Zhang Yang, Pan Zhenkui, Zhang Xing, Xu Fei, Zhang Li

Abstract excerpt

BACKGROUND AND OBJECTIVE: Recent studies indicated that Non-small cell lung cancer (NSCLC) patients with mutant K-RAS failed to benefit from adjuvant chemotherapy, and the cancer did not respond to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). These findings indicated that K-RAS gene status can be a biomarker to predict the sensitivity of EGFR TKIs. The aim of this study is to analyze...

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Identifiers

PMID: 20681447
DOI: 10.3779/j.issn.1009-3419.2010.06.007
PMCID: PMC6015157

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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