p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking.

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Article

p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking.

Cancer research - 1 Feb 1992

Suzuki H, Takahashi T, Kuroishi T, Suyama M, Ariyoshi Y, Takahashi T, Ueda R

Abstract excerpt

The p53 gene has been implicated as a tumor suppressor gene involved in the pathogenesis of lung cancer. Our previous study revealed that the p53 gene is frequently mutated with a distinct nucleotide substitution pattern in small cell lung cancer specimens in Japanese patients. In this study, we examined 30 primary, resected non-small cell lung cancer samples in Japanese patients using complementary...

Topics

Amino Acid Sequence
Analysis of Variance
Base Sequence
Carcinoma, Non-Small-Cell Lung
Codon
DNA, Neoplasm
Female
Genes, p53
Humans
Japan
Lung Neoplasms
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Molecular Sequence Data

Multivariate Analysis

Mutation

Neoplasm Staging

Odds Ratio

Source

Open in PubMed

Identifiers

PMID: 1310070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1310070-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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