Article
Pathological features and BRCA1 mutation screening in premenopausal breast cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2001
Chang J, Hilsenbeck S G, Sng J H, Wong J, Ragu G C
Abstract excerpt
PURPOSE: Risk calculations for carrying BRCA1/BRCA2 mutations are based on family history and the age of onset of cancers. However, women may carry these deleterious mutations without a strong family history. Additional criteria for risk estimation would be of value. It has been recently established that BRCA1-associated breast cancers are associated with poor tumor differentiation (TD3) and estrogen receptor...
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