Article
Major improvement in the efficacy of BRCA1 mutation screening using morphoclinical features of breast cancer.
Cancer research - 1 Mar 2000
Lidereau R, Eisinger F, Champème M H, Noguès C, Bièche I, Birnbaum D, Pallud C, Jacquemier J, Sobol H
Abstract excerpt
A family history of breast and/or ovarian cancer is the main criterion used in screening BRCA1 gene carriers. However, ascertaining a patient's family history is a difficult task, which significantly restricts the use of this parameter in clinical practice. Alternative individual criteria that can be used to identity BRCA1 gene carriers would, therefore, be of great value. In this context, it was recently...
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