Article
Novel indications for BRCA1 screening using individual clinical and morphological features.
International journal of cancer - 21 Jun 1999
Eisinger F, Noguès C, Guinebretière J M, Peyrat J P, Bardou V J, Noguchi T, Vennin P, Sauvan R, Lidereau R, Birnbaum D, Jacquemier J, Sobol H
Abstract excerpt
Since there is a lack of common family profile among BRCA1-gene carriers, and since the risk of being a mutation carrier is not limited to women with a family history of breast or ovarian cancer, multivariate statistical analysis using the logistic-regression model was carried out, to discriminate between sporadic cases and BRCA1-breast cancers (BRCA1-BCs), especially when information about the family history of...
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