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Article

The prevalence of BRCA1 mutations among young women with triple-negative breast cancer.

BMC cancer - 19 Mar 2009

Young S R, Pilarski Robert T, Donenberg Talia, Shapiro Charles, Hammond Lyn S, Miller Judith, Brooks Karen A, Cohen Stephanie, Tenenholz Beverly, Desai Damini, Zandvakili Inuk, Royer Robert, Li Song, Narod Steven A

Abstract excerpt

BACKGROUND: Molecular screening for BRCA1 and BRCA2 mutations is now an established component of risk evaluation and management of familial breast cancer. Features of hereditary breast cancer include an early age-of-onset and over-representation of the 'triple-negative' phenotype (negative for estrogen-receptor, progesterone-receptor and HER2). The decision to offer genetic testing to a breast cancer patient is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19298662
DOI: 10.1186/1471-2407-9-86
PMCID: PMC2666759

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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