Article
Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Sept 2008
Atchley Deann P, Albarracin Constance T, Lopez Adriana, Valero Vicente, Amos Christopher I, Gonzalez-Angulo Ana Maria, Hortobagyi Gabriel N, Arun Banu K
Abstract excerpt
PURPOSE: Mutations in the BRCA1 and BRCA2 genes confer greater risk of developing breast cancer. We determined whether tumor pathologic features and clinical features differ in patients with and without BRCA mutations. PATIENTS AND METHODS: Tumor pathologic features and clinical characteristics were examined in 491 women with breast cancer who underwent genetic testing for BRCA mutations between 1997 and 2006. A...
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