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Article

The proapoptotic protein Bad binds the amphipathic groove of 14-3-3zeta.

Biochimica et biophysica acta - 11 Jun 2001

Yang H, Masters S C, Wang H, Fu H

Abstract excerpt

Through interaction with a multitude of target proteins, 14-3-3 proteins participate in the regulation of diverse cellular processes including apoptosis. These 14-3-3-interacting proteins include a proapoptotic Bcl-2 homolog, Bad (Bcl-2/Bcl-XL-associated death promoter). To understand how 14-3-3 interacts with Bad and modulates its function, we have identified structural elements of 14-3-3 necessary for...

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Source

Identifiers

PMID: 11410287
DOI: 10.1016/s0167-4838(01)00202-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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