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Article

Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display.

Biochemistry - 21 Sept 1999

Wang B, Yang H, Liu Y C, Jelinek T, Zhang L, Ruoslahti E, Fu H

Abstract excerpt

The 14-3-3 proteins interact with diverse cellular molecules involved in various signal transduction pathways controlling cell proliferation, transformation, and apoptosis. To aid our investigation of the biological function of 14-3-3 proteins, we have set out to identify high-affinity antagonists. By screening phage display libraries, we have identified a set of peptides which bind 14-3-3 proteins. One of these...

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PMID: 10493820
DOI: 10.1021/bi991353h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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