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Article

14-3-3 regulation of cell spreading and migration requires a functional amphipathic groove.

Journal of cellular physiology - 1 Jan 2005

Rodriguez Luis G, Guan Jun-Lin

Abstract excerpt

The 14-3-3 proteins associate with many cellular proteins that participate in the regulation of various cellular events including apoptosis, the cell cycle, spreading, and migration. We have previously described that 14-3-3beta binds the beta1-integrin and overexpression of 14-3-3beta promoted increased cell spreading and migration (Han et al. [2001] Oncogene 20: 346-357). In this study, we find that mutation of...

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Identifiers

PMID: 15389601
DOI: 10.1002/jcp.20122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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