Article
Ras regulates the polarity of the yeast actin cytoskeleton through the stress response pathway.
Molecular biology of the cell - 1 Jun 2001
Ho J, Bretscher A
Abstract excerpt
Polarized growth in yeast requires cooperation between the polarized actin cytoskeleton and delivery of post-Golgi secretory vesicles. We have previously reported that loss of the major tropomyosin isoform, Tpm1p, results in cells sensitive to perturbations in cell polarity. To identify components that bridge these processes, we sought mutations with both a conditional defect in secretion and a partial defect in...
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