Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.

The Journal of cell biology - 12 Nov 2001

Adamo J E, Moskow J J, Gladfelter A S, Viterbo D, Lew D J, Brennwald P J

Abstract excerpt

The Rho family GTPase Cdc42 is a key regulator of cell polarity and cytoskeletal organization in eukaryotic cells. In yeast, the role of Cdc42 in polarization of cell growth includes polarization of the actin cytoskeleton, which delivers secretory vesicles to growth sites at the plasma membrane. We now describe a novel temperature-sensitive mutant, cdc42-6, that reveals a role for Cdc42 in docking and fusion of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to cdc42 GTP-Binding Protein, Saccharomyces cerevisiae
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exocytosis

Share to Fungal Proteins

Share to Genes, Fungal

Share to Golgi Apparatus

Share to rab GTP-Binding Proteins

Share to rho GTP-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 11706050
DOI: 10.1083/jcb.200106065
PMCID: PMC2198861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.PMID 11706050Read ↗

Exo-endocytic trafficking and the septin-based diffusion barrier are required for the maintenance of Cdc42p polarization during budding yeast asymmetric growth.Semantic proximity Read ↗

Cdc42 interacts with the exocyst and regulates polarized secretion.Semantic proximity Read ↗

Distinct Cdc42 protein levels differentially regulate polarized growth and cell fusion in Schizosaccharomyces pombe.Semantic proximity Read ↗

The Rho GTPase Rho3 has a direct role in exocytosis that is distinct from its role in actin polarity.Semantic proximity Read ↗

Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex.Semantic proximity Read ↗

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth.Semantic proximity Read ↗

The Cdc42p GTPase is involved in a G2/M morphogenetic checkpoint regulating the apical-isotropic switch and nuclear division in yeast.Semantic proximity Read ↗

Transbilayer phospholipid flipping regulates Cdc42p signaling during polarized cell growth via Rga GTPase-activating proteins.Semantic proximity Read ↗

Regulation of Gic2 localization and function by phosphatidylinositol 4,5-bisphosphate during the establishment of cell polarity in budding yeast.Semantic proximity Read ↗

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae cdc42p GTPase is involved in preventing the recurrence of bud emergence during the cell cycle.Semantic proximity Read ↗

Cdc42 regulates multiple membrane traffic events in fission yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.