Article
The class V myosin Myo2p is required for Fus2p transport and actin polarization during the yeast mating response.
Molecular biology of the cell - 1 Jun 2009
Sheltzer Jason M, Rose Mark D
Abstract excerpt
Mating yeast cells remove their cell walls and fuse their plasma membranes in a spatially restricted cell contact region. Cell wall removal is dependent on Fus2p, an amphiphysin-associated Rho-GEF homolog. As mating cells polarize, Fus2p-GFP localizes to the tip of the mating projection, where cell fusion will occur, and to cytoplasmic puncta, which show rapid movement toward the tip. Movement requires...
Topics
- Actins
- Alleles
- Cell Polarity
- Cytoskeletal Proteins
- Cytoskeleton
- Genes, Mating Type, Fungal
- Membrane Proteins
- Mutation
- Myosin Heavy Chains
- Myosin Type V
- Protein Structure, Tertiary
- Protein Transport
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Secretory Vesicles
- Tropomyosin
- rab GTP-Binding Proteins