Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport.

The Journal of cell biology - 1 Jul 1992

Liu H, Bretscher A

Abstract excerpt

Disruption of the yeast tropomyosin gene TPM1 results in the apparent loss of actin cables from the cytoskeleton (Liu, H., and A. Bretscher. 1989. Cell. 57:233-242). Here we show that TPM1 disrupted cells grow slowly, show heterogeneity in cell size, have delocalized deposition of chitin, and mat...

Topics

Chitin
Chromosome Deletion
Crosses, Genetic
Cytoplasmic Granules
Diploidy
Genes, Fungal
Genotype
Glycoside Hydrolases
Glycosylation
Kinetics
Mating Factor
Microscopy, Electron

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptides

Pheromones

Saccharomyces cerevisiae

Tropomyosin

beta-Fructofuranosidase

Source

Open in PubMed Open full text

Identifiers

PMID: 1629236
DOI: 10.1083/jcb.118.2.285
PMCID: PMC2290051

Genes

TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1629236-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport.PMID 1629236Read ↗

Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions.Semantic proximity Read ↗

The role of Myo2, a yeast class V myosin, in vesicular transport.Semantic proximity Read ↗

Ras regulates the polarity of the yeast actin cytoskeleton through the stress response pathway.Semantic proximity Read ↗

Mutations synthetically lethal with tpm1delta lie in genes involved in morphogenesis.Semantic proximity Read ↗

A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae.Semantic proximity Read ↗

The rho-GAP encoded by BEM2 regulates cytoskeletal structure in budding yeast.Semantic proximity Read ↗

The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.Semantic proximity Read ↗

Overexpression of MID2 suppresses the profilin-deficient phenotype of yeast cells.Semantic proximity Read ↗

Immunofluorescence localization of the unconventional myosin, Myo2p, and the putative kinesin-related protein, Smy1p, to the same regions of polarized growth in Saccharomyces cerevisiae.Semantic proximity Read ↗

LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum.Semantic proximity Read ↗

Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae.Semantic proximity Read ↗

Genes for directing vacuolar morphogenesis in Saccharomyces cerevisiae. I. Isolation and characterization of two classes of vam mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.