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Article

Regulated phosphorylation of budding yeast's essential myosin V heavy chain, Myo2p.

Molecular biology of the cell - 1 Apr 2006

Legesse-Miller Aster, Zhang Sheng, Santiago-Tirado Felipe H, Van Pelt Colleen K, Bretscher Anthony

Abstract excerpt

The tail of the yeast myosin V encoded by Myo2p is known to bind several receptors for cargo delivery along polarized actin cables. However, it is not known how Myo2p activity is regulated or how it selects between cargoes. Here we show that Myo2p is reversibly phosphorylated in vivo. A short peptide at the N-terminal end of the cargo-binding domain contains three residues contributing to single or doubly...

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Identifiers

PMID: 16467380
DOI: 10.1091/mbc.e05-09-0872
PMCID: PMC1415295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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