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Article

Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Feb 2003

Misu Kenjiro, Fujimura-Kamada Konomi, Ueda Takashi, Nakano Akihiko, Katoh Hiroyuki, Tanaka Kazuma

Abstract excerpt

During the cell cycle of the yeast Saccharomyces cerevisiae, the actin cytoskeleton and the growth of cell surface are polarized, mediating bud emergence, bud growth, and cytokinesis. We identified CDC50 as a multicopy suppressor of the myo3 myo5-360 temperature-sensitive mutant, which is defective in organization of cortical actin patches. The cdc50 null mutant showed cold-sensitive cell cycle arrest with a...

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Identifiers

PMID: 12589066
DOI: 10.1091/mbc.e02-06-0314
PMCID: PMC150004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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