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Article

The Ras/protein kinase A pathway acts in parallel with the Mob2/Cbk1 pathway to effect cell cycle progression and proper bud site selection.

Eukaryotic cell - 1 Feb 2004

Schneper Lisa, Krauss Alicia, Miyamoto Ryan, Fang Shirley, Broach James R

Abstract excerpt

In Saccharomyces cerevisiae, Ras proteins connect nutrient availability to cell growth through regulation of protein kinase A (PKA) activity. Ras proteins also have PKA-independent functions in mitosis and actin repolarization. We have found that mutations in MOB2 or CBK1 confer a slow-growth phenotype in a ras2Delta background. The slow-growth phenotype of mob2Delta ras2Delta cells results from a G1 delay that...

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Identifiers

PMID: 14871942
DOI: 10.1128/EC.3.1.108-120.2004
PMCID: PMC329503

Genes

MOB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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