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Article

Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway.

Molecular biology of the cell - 1 Nov 2003

deHart Amy K A, Schnell Joshua D, Allen Damian A, Tsai Ju-Yun, Hicke Linda

Abstract excerpt

Efficient internalization of proteins from the cell surface is essential for regulating cell growth and differentiation. In a screen for yeast mutants defective in ligand-stimulated internalization of the alpha-factor receptor, we identified a mutant allele of TOR2, tor2G2128R. Tor proteins are known to function in translation initiation and nutrient sensing and are required for cell cycle progression through G1....

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Identifiers

PMID: 14593073
DOI: 10.1091/mbc.e03-05-0323
PMCID: PMC266782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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