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Article

Mice lacking the Nkx6.2 (Gtx) homeodomain transcription factor develop and reproduce normally.

Molecular and cellular biology - 1 Jul 2001

Cai J, Qi Y, Wu R, Modderman G, Fu H, Liu R, Qiu M

Abstract excerpt

The Nkx homeobox genes are expressed in a variety of developing tissues and have been implicated in controlling tissue patterning and cell differentiation. Expression of Nkx6.2 (Gtx) was previously observed in the embryonic neural tube, testis, and differentiating oligodendrocytes. To investigate the role of Nkx6.2 in the control of cell specification and differentiation, we generated mice with null mutations in...

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Identifiers

PMID: 11390667
DOI: 10.1128/MCB.21.13.4399-4403.2001
PMCID: PMC87099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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