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Article

Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology.

Genesis (New York, N.Y. : 2000) - 1 Aug 2012

Arnes Luis, Leclerc Kevin, Friel Jessica M, Hipkens Susan B, Magnuson Mark A, Sussel Lori

Abstract excerpt

Nkx2.2 encodes a homeodomain transcription factor required for the correct specification and/or differentiation of cells in the pancreas, intestine, and central nervous system (CNS). To follow the fate of cells deleted for Nkx2.2 within these tissues, we generated Nkx2.2:lacZ knockin mice using a recombination-mediated cassette exchange (RMCE) approach. Expression analysis of lacZ and/or β-galactosidase in...

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Source

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Identifiers

PMID: 22539496
DOI: 10.1002/dvg.22037
PMCID: PMC3421046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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