Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EAAT1 and EAAT2 immunoreactivity in transgenic mice with a G93A mutant SOD1 gene.

Neuroreport - 25 May 2001

Sasaki S, Warita H, Abe K, Komori T, Iwata M

Abstract excerpt

Immunocytochemical and quantitative analyses were used to correlate the localisation of excitatory amino acid transporter proteins EAAT1, EAAT2 with time in spinal motoneurones of presymptomatic and symptomatic mice with the G93A mutant SOD1 gene. Specimens from age-matched non-transgenic wild-type mice served as controls. EAAT1 and EAAT2 immunoreactivity was well-preserved in the gray matter in both controls and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Excitatory Amino Acid Transporter 2
Share to Glutamic Acid
Share to Motor Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nerve Degeneration

Share to Receptors, Neurotransmitter

Share to Spinal Cord

Share to Superoxide Dismutase

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 11388411
DOI: 10.1097/00001756-200105250-00014

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EAAT1 and EAAT2 immunoreactivity in transgenic mice with a G93A mutant SOD1 gene.PMID 11388411Read ↗

Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice.Semantic proximity Read ↗

GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1.Semantic proximity Read ↗

Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice.Semantic proximity Read ↗

Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.Semantic proximity Read ↗

Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.Semantic proximity Read ↗

Morphological changes and selective loss of motoneurons in the lumbar part of the spinal cord in a rat model of familial amyotrophic lateral sclerosis (fALS).Semantic proximity Read ↗

Excitatory Amino acid transporter expression in the essential tremor dentate nucleus and cerebellar cortex: A postmortem study.Semantic proximity Read ↗

Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutase.Semantic proximity Read ↗

Change in superoxide dismutase 1 protein localization towards mitochondria: an immunohistochemical study in transgenic G93A mice.Semantic proximity Read ↗

Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS.Semantic proximity Read ↗

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease.Semantic proximity Read ↗

Endocannabinoids accumulate in spinal cord of SOD1<sup>G93A</sup> transgenic miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.