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Article

Change in superoxide dismutase 1 protein localization towards mitochondria: an immunohistochemical study in transgenic G93A mice.

Neuroscience letters - 25 Oct 2002

Ilieva Hristelina, Nagano Isao, Murakami Tetsuro, Shiote Mito, Manabe Yasuhiro, Abe Koji

Abstract excerpt

Localization of superoxide dismutase1 (SOD1) and mitochondrial glucose-regulated protein 75 (Grp75), were examined in the spinal cords of transgenic (Tg) mice expressing human mutant SOD1 protein (G93A) and wild-type (Wt) controls at 8, 20 and 32 weeks. SOD1 showed a progressive increase of dot-like deposits in the neuropil of anterior horn of Tg mice, and a late decrease of signal intensity in the white matter...

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Source

Identifiers

PMID: 12377383
DOI: 10.1016/s0304-3940(02)00917-5

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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