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Article

Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice.

The Journal of comparative neurology - 2 Feb 1998

Morrison B M, Janssen W G, Gordon J W, Morrison J H

Abstract excerpt

Transgenic mice with a G86R mutation in the mouse superoxide dismutase (SOD-1) gene, which corresponds to a mutation observed in familial amyotrophic lateral sclerosis (ALS), display progressive motor dysfunction leading to paralysis and premature death. In endstage SOD-1 transgenic mice, there is marked loss of spinal motor neurons and interneurons, accumulation of phosphorylated neurofilament inclusions, and...

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Identifiers

PMID: 9527542
DOI: 10.1002/(sici)1096-9861(19980202)391:1<64::aid-cne6>3.0.co;2-p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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