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Article

Endocannabinoids accumulate in spinal cord of SOD1<sup>G93A</sup> transgenic mice

20 May 2004

Abstract excerpt

Approximately 2% of amyotrophic lateral sclerosis (ALS) cases are caused by mutations in the super oxide dismutase 1 (SOD1) gene and transgenic mice for these mutations recapitulate many features of this devastating neurodegenerative disease. Here we show that the amount of anandamide (AEA) and 2-arachidonoylglycerol (2-AG), two endocannabinoids that have neuroprotective properties, increase in spinal cord of...

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PMID: 15189359
DOI: 10.1111/j.1471-4159.2004.02544.x

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