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Article

GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1.

Journal of the neurological sciences - 15 Jan 2002

Deitch Jeffrey S, Alexander Guillermo M, Del Valle Luis, Heiman-Patterson Terry D

Abstract excerpt

A decrease in expression of the glutamate transporter GLT-1 is thought to be responsible for the increase in extracellular glutamate observed in patients with amyotrophic lateral sclerosis (ALS) and in a transgenic mouse model of ALS. We examined protein levels of the glutamate transporters GLT-1, GLAST and EAAC1 in the G93A (SOD1) transgenic mouse model of ALS. GLT-1 was detected in two bands (72 and 150 kD)....

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Source

Identifiers

PMID: 11790392
DOI: 10.1016/s0022-510x(01)00656-6

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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