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Article

Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS.

The New England journal of medicine - 31 May 2001

Gao X, Nelson G W, Karacki P, Martin M P, Phair J, Kaslow R, Goedert J J, Buchbinder S, Hoots K, Vlahov D, O'Brien S J, Carrington M

Abstract excerpt

BACKGROUND: From studies of genetic polymorphisms and the rate of progression from human immunodeficiency virus type 1 (HIV-1) infection to the acquired immunodeficiency syndrome (AIDS), it appears that the strongest susceptibility is conferred by the major-histocompatibility-complex (MHC) class I type HLA-B*35,Cw*04 allele. However, cytotoxic T-lymphocyte responses have been observed against HIV-1 epitopes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11386265
DOI: 10.1056/NEJM200105313442203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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