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Article

Apolipoprotein E genotype and subcortical vascular lesions in older depressed patients and control subjects.

Biological psychiatry - 1 Oct 2003

Steffens David C, Trost William T, Payne Martha E, Hybels Celia F, MacFall James R

Abstract excerpt

BACKGROUND: Several studies have linked geriatric depression with cerebrovascular disease. The apolipoprotein E gene (APOE) epsilon 4 allele has been associated with a variety of late-life neuropsychiatric disorders, including Alzheimer's disease, vascular dementia, and depression. METHODS: The sample consisted of 145 elderly depressive individuals and 100 nondepressed elderly control subjects. After a...

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Identifiers

PMID: 14512206
DOI: 10.1016/s0006-3223(02)01782-1

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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