Article
Apolipoprotein-E and white-matter hyperintensities in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Jan 2000
Lavretsky H, Lesser I M, Wohl M, Miller B L, Mehringer C M, Vinters H V
Abstract excerpt
The authors conducted a follow-up study of 16 patients with late-life depression approximately 6 years after their initial assessment to evaluate the relationships between apolipoprotein-E (APO-E) status and white-matter hyperintensities (WMH). Ten patients had WMH at baseline, and four patients demonstrated an increase in WMH size over time. Three of four patients with the APO-E epsilon 4 allele demonstrated an...
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