Article
Association between white matter hyperintensity severity and cognitive impairment according to the presence of the apolipoprotein E (APOE) ε4 allele in the elderly: retrospective analysis of data from the CREDOS study.
The Journal of clinical psychiatry - 1 Dec 2012
Son Sang Joon, Lee Kang Soo, Lee Yunhwan, Baek Jong Hwan, Choi Seong Hye, Na Duk L, Seo Sang Won, Oh Byoung Hoon, Hong Chang Hyung
Abstract excerpt
OBJECTIVE: To investigate the effect of white matter hyperintensity (WMH) severity on cognitive function according to presence of the apolipoprotein E (APOE) ε4 allele. METHOD: From participants in a nationwide, multicenter, hospital-based cohort study of dementia by the Clinical Research Center for Dementia of South Korea (November 2005 to December 2011), data for 5,077 elderly subjects (mean [SD] age = 71.37...
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