Article
Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Oct 2007
Steffens David C, Potter Guy G, McQuoid Douglas R, MacFall James R, Payne Martha E, Burke James R, Plassman Brenda L, Welsh-Bohmer Kathleen A
Abstract excerpt
OBJECTIVE: Several studies suggest that depression is a risk factor for development of dementia in the elderly. In a study of older depressed individuals, the authors examined both neuroimaging and genetic factors in development of dementia. The authors hypothesized that change in subcortical gray matter and white matter hyperintensity volumes would be associated with development of dementia, as would presence of...
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