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Article

Effects of hereditary retinal degeneration due to a CEP290 mutation on the feline pupillary light reflex.

Veterinary ophthalmology - 1 May 2010

Thompson Stewart, Whiting Rebecca E H, Kardon Randy H, Stone Edwin M, Narfström Kristina

Abstract excerpt

OBJECTIVE: To understand how progressive rod cone degeneration due to a mutation in CEP290 affects the pupillary light reflex (PLR) in domestic cats. ANIMALS STUDIED: Domestic cats identified as either normal wildtype (WT; n = 6), or homozygous for the rdAc mutation in CEP290 and having early stage retinal degeneration (stage 2, S2; n = 4), or advanced retinal degeneration (S4; n = 6). METHODS: The effect of...

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Identifiers

PMID: 20500714
DOI: 10.1111/j.1463-5224.2010.00772.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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