Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample.

Schizophrenia research - 1 Sept 2010

Nieratschker Vanessa, Frank Josef, Mühleisen Thomas W, Strohmaier Jana, Wendland Jens R, Schumacher Johannes, Treutlein Jens, Breuer René, Abou Jamra Rami, Mattheisen Manuel, Herms Stefan, Schmäl Christine, Maier Wolfgang, Nöthen Markus M, Cichon Sven, Rietschel Marcella, Schulze Thomas G

Abstract excerpt

The aim of the present study was to investigate possible associations between schizophrenia and 13 SNP markers in COMT. No association was observed in 631 cases, 207 nuclear families, and 776 controls. A cognitive performance phenotype (Trail Marking Test) was available for a subgroup of the pati...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catechol O-Methyltransferase
Share to Cognition Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Family Health

Share to Genome-Wide Association Study

Share to Germany

Share to Neuropsychological Tests

Share to Schizophrenia

Source

Identifiers

PMID: 20643532
DOI: 10.1016/j.schres.2010.06.018

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20643532-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample.PMID 20643532Read ↗

No association of catechol-O-methyltransferase polymorphisms with schizophrenia in the Han Chinese population.Semantic proximity Read ↗

Meta-analysis of association between genetic variants in COMT and schizophrenia: an update.Semantic proximity Read ↗

Association study of catechol-O-methyltransferase gene polymorphisms with schizophrenia and psychopathological symptoms in Han Chinese.Semantic proximity Read ↗

The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons.Semantic proximity Read ↗

Association of catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population.Semantic proximity Read ↗

Association of the 3' region of COMT with schizophrenia in Taiwan.Semantic proximity Read ↗

Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia.Semantic proximity Read ↗

Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: a large-scale association study plus meta-analysis.Semantic proximity Read ↗

Association study between the rs165599 catechol-O-methyltransferase genetic polymorphism and schizophrenia in a Brazilian sample.Semantic proximity Read ↗

Functional catechol-O-methyltransferase gene polymorphism and susceptibility to schizophrenia.Semantic proximity Read ↗

No evidence for linkage between COMT and schizophrenia in a French population.Semantic proximity Read ↗

Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.