Article
Ethnicity delineates different genetic pathways in malignant glioma.
Cancer research - 15 May 2001
Chen P, Aldape K, Wiencke J K, Kelsey K T, Miike R, Davis R L, Liu J, Kesler-Diaz A, Takahashi M, Wrensch M
Abstract excerpt
In the United States and the San Francisco Bay Area, whites are nearly twice as likely as non-whites to develop brain cancer. To test whether prevalence and types of alterations in the p53 pathway in brain tumor development may explain some of this difference in risk, we have analyzed the p53 status of astrocytic gliomas from a population-based sample of cases within our San Francisco Bay Area Adult Glioma Study....
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