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Article

Molecular genetic alterations in gliomatosis cerebri: what can we learn about the origin and course of the disease?

Acta neuropathologica - 1 Dec 2005

Mawrin Christian

Abstract excerpt

Gliomatosis cerebri (GC) is a neuroepithelial neoplasm with extensive infiltration of large parts of the brain. Recent data showing the involvement of TP53 mutation or nuclear protein accumulation in some cases have linked the astrocytic phenotype of the tumor cells to TP53 alterations frequently found in common astrocytomas. However, the frequency of these alterations is low, and other molecular genetic changes...

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PMID: 16222524
DOI: 10.1007/s00401-005-1083-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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