Article
The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma.
Blood - 15 Dec 1995
Du M, Peng H, Singh N, Isaacson P G, Pan L
Abstract excerpt
The genetic mechanisms underlying the genesis of low-grade mucosa-associated lymphoid tissue (MALT) lymphomas and their transformation into high-grade lymphoma are poorly understood. p53 inactivation, commonly caused by mutation and allele loss, has been shown to play an important role in the ear...
Topics
- Alleles
- Base Sequence
- Codon
- DNA Mutational Analysis
- DNA, Neoplasm
- Disease Progression
- Exons
- Genes, p53
- Humans
- Intestinal Neoplasms
- Intestine, Small
- Lymphoma, B-Cell, Marginal Zone
- Lymphoma, Non-Hodgkin
- Molecular Sequence Data
- Neoplasm Proteins
- Polymorphism, Single-Stranded Conformational
- Salivary Gland Neoplasms
- Sequence Deletion