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Article

Evaluation of p53 protein expression in Barrett's esophagus by two-parameter flow cytometry.

Gastroenterology - 1 Apr 1992

Ramel S, Reid B J, Sanchez C A, Blount P L, Levine D S, Neshat K, Haggitt R C, Dean P J, Thor K, Rabinovitch P S

Abstract excerpt

Barrett's esophagus is a condition in which the normal stratified squamous epithelium is replaced by metaplastic columnar epithelium that predisposes to the development of esophageal adenocarcinoma. Neoplastic progression in Barrett's esophagus occurs by a multistep process associated with genomic instability and the development of aneuploid cell populations. p53 protein overexpression and allelic deletions on...

Topics

Adenocarcinoma
Barrett Esophagus
DNA
Esophageal Neoplasms
Esophagus
Flow Cytometry
Genes, p53
Humans
Mutation
Tumor Suppressor Protein p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1551529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1551529-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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