Article
Presence of Lps(d) mutation influences cytokine regulation in vivo by the Mycoplasma arthritidis mitogen superantigen and lethal toxicity in mice infected with M. arthritidis.
Infection and immunity - 1 Jun 2001
Mu H H, Sawitzke A D, Cole B C
Abstract excerpt
The Mycoplasma arthritidis mitogen (MAM) superantigen (SAg) is a potent activator of human and murine cells and is produced by an organism that is a cause of acute and chronic arthritis of rodents. It is phylogenetically unrelated to other bacterial SAgs and exhibits a number of unique features. We recently demonstrated that MAM differentially regulates the cytokine responses of different mouse strains following...
Topics
- Animals
- Arthritis, Infectious
- Cytokines
- Gene Expression Regulation
- Interleukin-12
- Lipopolysaccharides
- Macrophages
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mitogens