Article
Genomic composition and allelic polymorphisms influence V beta usage by the Mycoplasma arthritidis superantigen.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1993
Cole B C, Balderas R A, Ahmed E A, Kono D, Theofilopoulos A N
Abstract excerpt
The Mycoplasma arthritidis superantigen (MAM) is produced by an organism that causes systemic disease in rodents leading to chronic proliferative arthritis. MAM is a typical superantigen that requires presentation to T cells by MHC molecules without processing and T cell recognition of MAM occurs through the V beta chains of the TCR. Several major findings are presented here. First, different MAM-MHC class II...
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