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Article

Genetic control of the innate immune response.

BMC immunology - 26 Jun 2003

Wells Christine A, Ravasi Timothy, Faulkner Geoffrey J, Carninci Piero, Okazaki Yasushi, Hayashizaki Yoshihide, Sweet Matthew, Wainwright Brandon J, Hume David A

Abstract excerpt

BACKGROUND: Susceptibility to infectious diseases is directed, in part, by the interaction between the invading pathogen and host macrophages. This study examines the influence of genetic background on host-pathogen interactions, by assessing the transcriptional responses of macrophages from five inbred mouse strains to lipopolysaccharide (LPS), a major determinant of responses to gram-negative microorganisms....

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Source

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Identifiers

PMID: 12826024
DOI: 10.1186/1471-2172-4-5
PMCID: PMC194878

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TLR4
ARC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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