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Article

Retinoic acid receptor alpha (RAralpha) Mutations in Human Leukemia.

Leukemia & lymphoma - 1 Oct 2000

Parrado A, Chomienne C, Padua R A

Abstract excerpt

The retinoic acid receptor alpha (RARalpha) plays a central role in the biology of the myeloid cellular compartment. Chromosomal translocations involving the RARalpha locus probably represent the malignant initiating events in acute promyelocytic leukemia (APL). Recent studies that identify novel interactions between RARalpha and the nuclear receptor co-activators and co-repressors, new functions of the oncogenic...

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PMID: 11342307
DOI: 10.3109/10428190009065826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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