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Article

c-Myc Is a Critical Target for C/EBPα in Granulopoiesis

1 Jun 2001

Abstract excerpt

CCAAT/enhancer binding protein alpha (C/EBPalpha) is an integral factor in the granulocytic developmental pathway, as myeloblasts from C/EBPalpha-null mice exhibit an early block in differentiation. Since mice deficient for known C/EBPalpha target genes do not exhibit the same block in granulocyte maturation, we sought to identify additional C/EBPalpha target genes essential for myeloid cell development. To...

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PMID: 11340171
DOI: 10.1128/mcb.21.11.3789-3806.2001

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c-Myc Is a Critical Target for C/EBPα in GranulopoiesisPMID 11340171Read ↗

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